A crystallographic view of the molybdenum cofactor †

Molybdenum Cofactor Biology and Disorders Related to Its Deficiency; A Review Study

Background: Molybden, as a vital and essential micronutrient is directly involved in the metabolism of other elements including carbon, sulfur, and nitrogen. Molybdenum alone is not biologically active unless it binds to specific cofactors. Except for the bacterial nitrogenase, which contains molybdenum-Iron complex, molybdenum cofactor (Moco) is considered as the bioactive component placed in ...

Molybdenum-cofactor-containing enzymes: structure and mechanism.

Molybdenum-containing enzymes catalyze basic metabolic reactions in the nitrogen, sulfur, and carbon cycles. With the exception of the nitrogenase cofactor, molybdenum is incorporated into proteins as the molybdenum cofactor that contains a mononuclear molybdenum atom coordinated to the sulfur atoms of a pterin derivative named molybdopterin. Certain microorganisms can also utilize tungsten in ...

Dehydrogenation, disproportionation and transfer hydrogenation reactions of formic acid catalyzed by molybdenum hydride compounds† †Electronic supplementary information (ESI) available. CCDC 1028432. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc03128h Click here for additional data file. Click here for additional data file.

Establishment of molybdeum cofactor detection system in Escherichia coli

In the current study, in order to verify the presence of bacterial Molybdenum cofactor, an indirect approach was made by showing the activity of BisC enzyme as a reporter gene. The activity of the BisC enzyme is dependent to Bis-MGD cofactor. BisC enzyme converts biotin sulfoxide to biotin under abiotic stress condition and it can also reduce TMANO and because of this property it was applied on...

Mixed-ligand complexes of paddlewheel dinuclear molybdenum as hydrodehalogenation catalysts for polyhaloalkanes† †Electronic supplementary information (ESI) available: Experimental details for the synthesis and characterization of Mo2 complexes, kinetic analysis of the reactions, 1H NMR spectra of the catalytic reactions, identification of the products, CV of selected Mo2 complexes, and crystal data for 7a (CCDC 1046579), 9a (CCDC 1046580), 10a (CCDC 1046581), and 11a (CCDC 1046582). CCDC 1046579–1046582. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc00721f